SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7e66fb322fab8ea0b247668bb07eafb845a4c9c2ee9238103d3f3c1b7410449' 
  AND token = 'Qrk7hmg3p4z61vAyPU1wIFCswBMDh3Ti0qCfwLUlauE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}