SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ebcf344f99e5cfc87ad39f9f0ace9faf60a57917688d35f188675b41c502351' 
  AND token = '1m/3TUK+0IZGwuW1dCcwQiLqiDo07Uw4ILSNmKwuJPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}