SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f17986e2648d0187c601ae63d17b5951282c0367baa76d42e5cf013a4cfb7e' 
  AND token = 'c/KJ6R3rpiyDNBoIwLAgNBCJHlgalE6P7VnuXBD2XfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}