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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8666a2cc202868e9f2508f5d0732ab57d03545befac9c1678ab937e7e9c762cb' 
  AND token = '9tCs794TFFY4GgCitih/0W2NQ1ZgQzA1o9s2UuSjTNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}