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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd73adf1c7de0e46d2730e59fd11bc419eec43c14f0ed10d40f44d47c9e363779' 
  AND token = 'EF7qiP4El8cBdPyFOggShBnYu7zkjuKCvPSC57/Li4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}