SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241354d7b3472b33d47039809701790756f3caa6db724a0a5ed12584f1bfb4c2' 
  AND token = 'jsfYiaszDj/hJS2dU7cfbeYIu74caBLxS2xWnB9S9gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}