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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d731a6998d489eea69fac991af3119ee78a62f2ddee80fd3012aa9059492c8d' 
  AND token = 'OJpAM8Q0vBUqsy4a7nvQg1z9N8EdKhT2JwBblVBfXV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}