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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e068b3c4e33a88aa3bb910a5935b227f81f8a68d199bddede1754f0e1cc4e47' 
  AND token = '+/ebhjaL95VKEPx8GzXprWGTjot8EbYc/FfTRAoRd+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}