SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5adf534c0b711c4a5f46509758f6577eca7773369d4788ede30e863ebb8d9d67' 
  AND token = 'DPGiHCR4uRSntZYwVg3agk1vhUg54+ekADLaYdXyiT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}