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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d0da0ccbf393c26f18c8c89a45af70aae2915c3595a112cd8af46fcfdd1425' 
  AND token = '/EbqlxspVxx8H4JtGrPyHesOFB4UCNrwfdx5aZlCG/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}