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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a7c72b63b3d47b81ec81991a40ec13e8e4c073ddbf339da71e37fd17dc18ab' 
  AND token = 'fI/6xGf2kmCS47zQIvZSEd2XshlzDrBXVjgH29/GTuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}