SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de8060227bb03fc92af42d176eb8eea99ca2cba9f155e0215266d75b38d69b9' 
  AND token = 'VNPRAabixYvqNI3Zpz7PQpvHhtZ2BiZUcmzNJH+p8q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}