SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5afa531fe81e4ac37f7ff0e5a34c70ee3c71d03cd945e08015ae1bfeb25c98' 
  AND token = 'Ix40bPNUb+CVFcPNx+H514OCMpETOPCL2pMzU8RqlCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}