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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcf83c607e33b3b0d19d432e5c5bbcbabae72733fa5d075aeed9c3849f5c4112' 
  AND token = 'pzDZRhWD4oVZqm93dR3GtWQ+aOMCAMHZ2ZNadpal6mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}