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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4d4fe7dae14a0cc668293829e07cfc2fb6e560896ccc44e1b59f28b2a0bd6e' 
  AND token = 'JSZFiygqYmEFRM9kvwhz5b5JwxJwOvZLhaobgaXzzrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}