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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deff81fbd38e068d879c3359e006d6da20c36b6e4046e21c735976c7d4bf08e4' 
  AND token = 'oe9LfAmZEl5abJfMjFvHFYUZefvh47I/91eqqa0Aci0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}