SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4bbcb7af22f90bfcc9cff77065ada85a1b22235443798f2c0e7eb67a339615' 
  AND token = 'sji49xgCtrJ8sGZh5BcSOIyI5/mMln59C947I9HE1rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}