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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622b96939932628fb4b81de0bed6a6ca884d81ad199d85c5179ce268b17a2c81' 
  AND token = 's8OERU4CWp+OB9eBznNuOZ0pUIVe2WuNG94Uq6niNsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}