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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e355383f6d154b21344b5c5173d332387895d50a7d6e2f83d0a63c208e97cf16' 
  AND token = 'qkyKkQVGKO90UWKcAZIoWcL9KEMBwQRdKMYXo7ViQHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}