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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1646b7debed709765458c3f6ba24bcbcd3ba034140f1dd2ffd81dbc0d5faac67' 
  AND token = 'rlx9DWGTtBgwLsXsFJplhcLTUT3bCx+GaD12gWTM/Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}