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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a8d39b060661c900f5b93bdc2d04b8a87bd2d62a84810084bd309a6f66d07f' 
  AND token = 'h4y/AC5f3JuKvlTjydZ+iPpY4IErJ/6xlsbTAYdhTZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}