SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94dd8288c002c8f0ab7839a679b3f8e488fa63591b29cdd5b0d9fe3a0eb738df' 
  AND token = 'XzWcu7Ja+kWUoc/CTQdgtWURuOg7M62yYjcSzeCyXi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}