SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef9ec6336fe3ffbc5777ee1ad7b28218bfc293802be3e43795b13f72bbb8e48' 
  AND token = '6Bdb6xJ1pcKJazToPS/M9o5hXciPSkGzoCx5q5aNrVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}