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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6565e9abf567e1b56681db58cda5b484a845e610e7b163f7cde184c37ce51b8d' 
  AND token = 'jmseV1Sas9uWnbxE9VMPNKN7yZk2s/hISMFgr1H3cHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}