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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad3d82fbc22f0deb09e831f2cd1aba49b32b2b05c59881e8288d19d2591a39dc' 
  AND token = '4rZuxqY0liloedcLPT/F3jPNXuLF20MnLu0Ehjt5R0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}