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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9292d1dcd9303ac01da1aa52f7b207626e6455cce0a40d64769c0e6bc7880faa' 
  AND token = '+I1t5Kar2+FYYCkAfKtNi4b8EgjY1ImFzHuFe6e99Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}