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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e556b6b811f8f9fe8c57aa0f7c4675627347ecb532c2fa89393c0865a6a4286e' 
  AND token = 'Am83WHGBFDsTIerVQc3/9mwMhCnNzMj4B55f38qTom8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}