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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80de7e3481b3059d70085b608110df819b1cc02a51401a566aa8337ea2b972dd' 
  AND token = '4Z9OSyx18j5KqQapw+IbJCoztOCRJZG6LnO0I7zQu+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}