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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b6f480a54551bf785e2efa6e3687bf27a5eb5e7c792b8c05991c8ebf45cb749' 
  AND token = 'de7zcDYGbgmmhQB7N3QkrBjMZlNk3iOkhrFwkOmR9Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}