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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3c4d3034fc2d54b7f55e0fed886bdb13fdf18ddaf267a7724923ffc775fc8c' 
  AND token = '/MZ2uAkrGLTh0hxvoz1sqf0gcA4E8ViKiY88hF0S1SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}