SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22095520e05711b1b3e88435991a2055e170c28bb1112f915d50a6fcc6b4be43' 
  AND token = 'IAJCz9ieL32htu8V7ynHhkvB7iHoVBTtdoqgFTlqVp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}