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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3857dd5a6d4443e261018be29cebaf6c68caefade71d25a7b15b1fed11c97bd2' 
  AND token = 'qbl+2/QoVfJh1GS5649QNkqjXES7P6xEC9vU/IjNo9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}