SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61b15c252c182d4d2db0cc6374d3d6b8076178b859e24f8da3d6e73cf66fab6b' 
  AND token = 'M0A1hVQTTIjZtsMk+yJ1c8avTOiNXyN3aaocUk2Kg8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}