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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddb25eb222d39ab94b334ce8f12eecb2e9a920dfd101ec58e998882076081f5f' 
  AND token = 'HS1Z4cE23lM1Gp8NhkMC7dBpK0LXYkUWBnDhPgKo0so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}