SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '044feb7b5171aac10d77cf5febfea9dfb1da1b80738931edfdfa2366962d7f53' 
  AND token = 'AbBGziR4vXfWaE8GL4/mvcSmjH7b78YSmvbmUxBJCuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}