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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f52f090965ecde65988ac6be033a0bfc98f01198e0729c9f4cf8e5b75a145d' 
  AND token = 'v6HPtnKxNns8n3tDWKxidCgQ1UkLOFyTFMHtljcIxv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}