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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2979ffe0634a5b414eaa21490f00c469c5e21c1f0af9f87207968cbb569763d1' 
  AND token = 'dMk6C6ZnGTNBhxcLR+1AuopEhgpy/3+gt1oOFcu2HoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}