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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bfd42524d2936c145b02256f5aa1af2233c7a05a1d4f605d78bfa1775142d5c' 
  AND token = 'Qf+CYvNqtcjVhYt5y5mzJIcm7/nXUU6mcjt32Q3czsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}