SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '126342a1825e602abc619e154f024fa79af33bd6a0fd9fe1457271da4dca6685' 
  AND token = '5/pIFoMEE5nvRWhv6tTRpU5wOPOrERaRsX6qXBaBJQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}