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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f2e2bb2c18796c91fb6054b3c99830a53cc0547bc2e84edf2f903b8814fbfac' 
  AND token = 'CVPOxvwr4oTxQ9qq03goewVMdCTZenrKXQCL6UcB+F4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}