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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c0d1278c45cee50153a56906f791e7867ba7ff8f46eb981b635787bb5fd2856' 
  AND token = 'dCPdZV2fgLMzh4+5AiHi6qZwkTEk44mCBg6w0f4I8m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}