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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b77702cf1690c1fab1ac86b4f3e57bc73f4a71cec88ca4de3f0638b75be4345' 
  AND token = 'XpePb4qlo5U0tt1vmWmNJINeGCkEp/c3UelrVO4ZT3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}