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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492f28f581642b2f9f48fda6c4543e962c5f20f1524d45e43024d08a39221366' 
  AND token = '9HX31eX0BmZBhNnm2VBAtEVLKvWj/jXkkml7zZT0h4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}