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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f5453331d4fac87481f471d18dc7cbdf0d187aa59fecae5502207fd223e0aed' 
  AND token = 'TehwcZwW9AYTUN8OkvBQydgOYdkW84uFS41bBUt0e8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}