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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c79c8cf70f4b21961d04631fb0c17b642a6b8a4d27ddab9b9283a4e744b51f' 
  AND token = 'N4EQTRDW+caRXG2eAR7vEwpsCJnyCjF/D2eJzv58t3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}