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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a25ac747af0e4dbfe1e978b09aabdf5ab63bde26cd2e72a78bc2ed5f78fa1a' 
  AND token = 't/h0KYYKU1DCcec9UsWD4b4r4eVe33Oby7vX1P8MCCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}