SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '882b4ef43ed7bffcaa3134ee9849001c61133bc7d74f4cb4df2f2a905bf2beaa' 
  AND token = 'mqejf1+l+2aj4cj/txRAH15dq18/yteMZf8rVSiFh1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}