SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053dfd5c0548bc2c9aafdf6d451c84ff65cc39013449afc1d2ff289af78de423' 
  AND token = 'OgidFUUCrKM5HMRMFzn+jhuzDPYG6J5zo6vEAkkyUyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}