SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7854b09e711afbd2e5daf613db1200d2cba2fab296bf9e8cbbe2da292c1c83b9' 
  AND token = '2d0OkhHBxIo+8zC8sBnNDquvpy+312+DQGA0UMiPOzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}