SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fbb4feb36710ad500f98e542d1bab89626b6dbcb3d9493a31bad9467c767092' 
  AND token = 'eRXFicQwUQG7TsrV2YypXzo1rDYFaTuGL6iZ3VcdkmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}